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Therefore, miRNAs can influence molecular signalling pathways and regulate many biological processes in health and disease.
Characterization of the key molecular signalling pathways revealed FGF-iPSCs to depend on the Activin/Nodal and FGF pathways, while signalling through the JAK-STAT pathway is not required for FGF-iPS cell maintenance.
Yet, still very little is known about the molecular signalling pathways involved in TNF-induced angiogenesis.
Few studies, however, have attempted to coalesce these various data to identify canonical molecular signalling pathways.
Bone formation during development and growth relies on a number of molecular signalling pathways and their complex interactions [ 18].
Dysregulation of molecular signalling pathways involving transforming growth factor β and SMAD pathways have been reported to induce fibrosis and also tumourigenesis [ 45].
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The present work is concerned to model the molecular signalling pathway for vasodilation and to predict the resting young human forearm blood flow under heat stress.
The mechanistic electronic modelling technique has been designed and implemented using MULTISIM 8.0 and an assumption of 1 V/°C for prediction of forearm blood flow and the digital logic has been used to design the molecular signalling pathway for vasodilation.
Most of the therapeutic targets are critical molecular signaling pathways associated with development of disease.
Modern chemotherapy targets discrete molecular signaling pathways to achieve an anticancer effect.
There have been few efforts to understand or engineer the molecular signaling pathways that dictate the efficacy of gene transfer.
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