Epithelial-mesenchymal transition (EMT), which can be caused by aberrant tyrosine kinase signalling, marks epithelial tumour progression and metastasis, yet the underlying molecular mechanism is not fully understood.
The endocannabinoid system is a molecular signalling network that plays a key role, like a symphony conductor -- more of this signal, less of this signal, in maintaining healthy homeostasis and equilibrium in our bodies.
This model captures the functional essence of histone marks as molecular signals that need not only to be 'written' but also to be 'read' by the appropriate machinery.
In the absence of nucleation sequences, DNA methylation (in addition to other epigenetic marks) serves as a molecular signal that guides reestablishment of the repressive chromatin structure following cell division.
This finding strongly suggests that the molecular signals that accompany inflammatory demyelination in either region are different, inducing marked accumulation of small HSPs in astrocytes in the WM but not in the GM.
"There are molecular signals that allow certain types of training," he said.
Our cells "write" epigenetic changes into our DNA in response to changes in the environment using various molecular signals.
This prompted them to theorize that NKB is the molecular signal telling the brain that the fetus is not getting sufficient blood.
He and his colleagues hope to figure out the molecular signals that tell younger people to build fast twitch muscles and older people to build slow twitch ones.
Further work is going on molecular signaling.
