Sentence examples for molecular screening strategy from inspiring English sources

A functional gene-based molecular screening strategy was used to target nonribosomal peptide synthetase (NRPS) in endophytes, it was found that the isolated endophytes are capable of producing a plethora of peptides.

Using a molecular screening strategy, we identified one critical coding-change variant in the MAVS gene which significantly altered function.

28 However, interpretation of a result should always take into account the sensitivity of the molecular screening strategy.

Given the proportion of all breast/ovarian cancer families in our population attributable to recurring mutations, a cost-effective stepwise molecular screening strategy of BRCA1 and BRCA2 may be applied in the future.

Further hrHPV subtype analysis may clarify type-specific correlation with POU4F3 methylation, which may be useful in estimating the impact of molecular screening strategy using HPV detection followed by methylation triage in post-vaccination era.

In some populations or ethnic groups, founder mutations form a sufficient proportion of the total to justify the adoption of specific molecular screening strategies.

Our combined molecular screening strategies have improved the overall throughput of our gene-knockout facilities and have broadened the types of mutations that we and others can identify.

We also demonstrated the specificity of the spectrum of LDLR gene mutations in the French population when compared to other countries, thus underscoring the requirement of specific national molecular screening strategies.

On the basis of the initial ALK example, we then extended our analyses to broadly explore the factors influencing the cost-effectiveness of different molecular screening strategies for targeted anti-cancer drug sensitivity biomarkers in general.

DNA-based assays are often more robust than RNA-based assays, and whereas the mutation spectrum causing TSG inactivation is usually diverse (which limits the utility of mutation-specific detection strategies for tumor screening programs), TSG inactivation by promoter hypermethylation provides a more homogeneous target for molecular screening strategies.

In several populations or ethnic groups, distinctive founder mutations form a sufficient proportion of the total to justify the adoption of specific molecular screening strategies (Levy-Lahad et al, 1997; Peelen et al, 1997; Thorlacius et al, 1997; Moller et al, 2001).