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These accessible cells could also be ideal for molecular screening based on gene expression if their mRNA can be isolated and is representative of the expression profile of the underlying tissue.
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In this study, we performed a molecular screen, based on PCR amplification of 16S rDNA, to identify bacterial associates of diverse Camponotini species.
Large-scale molecular RNA virus screening, based on host nucleic acid depletion, sequence-independent amplification, and sequencing of partially purified viral RNA was performed on nucleic acids isolated from 10 respiratory tract swab samples from pigs (4 – 6 ).
To circumvent the issue of lead compound toxicity, we performed screening based on molecular docking using structural databases of medical compounds.
In polyploids the effect of mutations in single homoeologues is often masked by inherent genetic redundancy; therefore forward genetic screening for mutations requires extensive screening based on effective isoenzymatic or molecular markers.
The soft ionization promoted by the APCI source allows effective and wide-scope screening based on the investigation of the molecular ion and/or protonated molecule.
Therefore, in silico screening, based on different algorithms implemented for molecular docking, to predict P-gp inhibitors has paved the road to a rational drug design and screening process.
- Co-crystal screening based on mixing enthalpy.
The frequency of germline mutants in G1 was sufficient to be used for gene targeting relying on a screen based solely on molecular methods.
This finding further suggests the possibility of developing a molecular screen for autism based on expressed biomarkers in peripheral blood lymphocytes, an easily accessible tissue.
Embryos were screened based on isl1 expression.
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