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In addition, we did not observe desynchronization of molecular rhythms among the sLNv as might be expected if communication were disrupted.
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The uncoupling of sLNv molecular rhythms from behavioral rhythms clearly demonstrates an output function for PDF in pacemaker neuron function.
The role of these molecular rhythms in glial function is unknown.
Circadian clocks govern daily physiological and molecular rhythms, and putative rhythms in expression of xenobiotic metabolizing (XM) genes have been described in both insects and mammals.
Other studies suggest that molecular rhythms are entrained by maternal rhythms just before birth even if the rhythms are difficult to measure until after birth [35], [36], [37], [38].
We first examined the molecular rhythms in those clock neurons that normally co-express PDFR and CRY.
However, we report three additional defects to the molecular rhythms in these critical pacemaker types, not previously reported.
In both studies, the behavior and molecular rhythms were retained in double mutant combinations but with altered phases.
The roles of circadian clock-controlled molecular rhythms in adapting organisms to the environment are only beginning to be explored.
However, the role of neural activity and membrane events in molecular rhythms in the fruit fly Drosophila is unclear.
The loss of per function disrupts behavioral and molecular rhythms in flies [ 10, 11, 13].
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