Sentence examples for molecular response groups from inspiring English sources
Similar numbers of chromosomal aberrations were observed in the diverse molecular response groups (Fig. 1B).
Lesions that were present in more than one patient were distributed over all three molecular response groups with no significant differences in their frequencies (Fig. 1C).
We observed similar median times to molecular response in both groups (442 and 423 days, respectively).
Finally, Takahashi et al. [ 26] showed that the SLC22A1 A1222G polymorphism (rs628031), which leads to Met408Val replacement, is associated with molecular response in the group of patients treated with IM doses lower than 400 mg.
Switching to 2GTKIs improves responses from 45% to 75% of complete cytogenetic response (CCyR) and from 15%to45%5% of major molecular response (MMR) in the group without molecular response 1 (MR1) at 3 months and from 70%to87%7% in CCyR and from 52%to87%7% in MMR in the group with MR1.
This approach is increasingly important also for the BCR/ABL-negative CMPD as realized by an international working group proposing cytogenetic and molecular response criteria in CIMF [ 64].
Median TTP in the group of patients, who lost their molecular response was 5 months.
Proteins of the LEA superfamily are part of the molecular response to this stressful environment [ 4] and are classified into groups based on amino acid sequence motifs [ 5].
Thus, the increase of active gelatinases detected on contralateral side muscles, in the experimental group (14 and 26 days), indicated a molecular response of the extracellular matrix.
Five patients achieved MMR, as the best molecular response, with median time 1.1 months after HCT, and this group included one patient in early post-transplant period, one who died due to aGvHD and three patients who lost this response.
This revealed considerable heterogeneity in the molecular response to glucocorticoids in patients into at least 2, and possibly 4 different groups (green bars, Figure 2), which may represent different modes of response to glucocorticoids in patients.
