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Phases were calculated using the molecular replacement program PHASER [35] using the kinase domain (pdb accession 1MP8) [36] as molecular search probe.
The DX structure was solved by use of the 18-19 as the search model using the molecular replacement program MOLREP [41].
Utilizing the maximum likelihood based molecular replacement program PHASER [3], MrGrid enables the user to retrieve and manage the results of tens to hundreds of MR calculations quickly and via a single web interface, as well as broadening the range of strategies that can be attempted, increasing the likelihood of success.
The structure was determined using the molecular replacement program Phaser 2.1.4 in the CCP4 6.1.13 suite.
The crystal structure was solved by the molecular replacement program Phaser [ 15] using the MJ0927 coordinates in P21 form as the template.
All diffraction data were processed using the HKL2000 suite, and the crystal structures were solved using maximum likelihood molecular replacement program Phaser in the PHENIX software suite.
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For example, if the crystal is orthorhombic P, Laue group mmm, and only the Sohncke space groups need to be considered, a molecular-replacement program can be asked to test all eight possibilities.
The structure was solved by molecular replacement using program PHASER [50] and refined to an R-value of 19.3% (Rfree = 22.5%) and good geometry (Table 1).
Initial phases were obtained by molecular replacement (CCP4 program M olrep [ Vagin, 1997]) by using an Aurora A kinase structure (PDB ID 1MQ4) as a search model.
The structure of the DYNLL2/Ac-SRGTQTE peptide complex was solved by molecular replacement using the program PHASER [73] of CCP4 6.1.2 Program Suite [74], [75].
The initial phases were determined by molecular replacement with the program Molrep49 using h3MST (PDB ID: 3OLH) or the determined m3MST structure as a search model.
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