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Structures were solved by molecular replacement and refined with the Phenix suite40 or Buster41.
The structure of the IL-1α/SL1067 complex was solved using molecular replacement and determined at 2.10 Å.
The structure for the wild-type protein in another lattice was solved by molecular replacement and extended to 1.6 Å resolution (type 2a, in P63 lattice; Fig. 1c).
The apo form of the canine enzyme was solved by molecular replacement and refined at a resolution of 3 Å.
There have also been key developments in software, and in molecular replacement and phase extension methods designed to facilitate the process of structure determination.
Molecular replacement and refinement were performed using CCP4 and the carbohydrate binding properties were described by affinity assays and computational docking.
The structure of the corresponding complex was solved at a resolution of 2.5 Å using molecular replacement and constitutes the first reported structure of a human ephrin receptor bound to an antibody.
"Remarkably, Foldit players were able to generate models of sufficient quality for successful molecular replacement and subsequent structure determination.
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The structures are homologous to that of wt-KaiC and diffraction data were phased using the molecular replacement technique and the KaiC structure with PDB ID code 3DVL [19] [19].
The BARD1 BRCT repeat structure was solved using molecular replacement methods and refined to 2.1 Å resolution (see Materials and Methods).
The crystals diffracted to a resolution of 1.8 Å, and the structure was solved by a combination of molecular replacement (MR) and SAD, by exploiting the anomalous signals of the tungsten atoms.
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