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Within cells, interactions between metabolites, proteins, or genes define a web of molecular relations which have well-defined organization.
The Supplementary Materials provide additional tables with detailed molecular relations for further pathway/disease combinations across different databases.
Molecular relations (protein-protein and protein/DNA interactions) were connected based on SysBiomics platform (http://biomine.cigb.edu.cu/sysbiomics/).cigb.edu.cu/sysbiomics/
The user must first generate visualization data with a preferred data mining algorithm and then upload the resulting data into the visualization package for graphic visualization of molecular relations.
The algorithm that counts the number of overlapping molecules and/or molecular relations between the extracted network and the canonical network identifies the canonical network showing the most statistically significant contribution to the extracted network.
The algorithm counting the number of overlapping molecular relations between the extracted network and the canonical pathway makes it possible to identify the canonical pathway showing the most significant contribution to the extracted network [ 12, 17].
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Molecular relation of strains was determined by using pulsed-field gel electrophoresis (PFGE) after digestion of genomic DNA with restriction endonuclease Sma1 (Gibco BRL, Promega, Madison, WI) (13 ).
The Venn diagram was constructed by using the freely available software system R (http://www.r-project.org) in order to visualize the grade of molecular relation (common genes/proteins) between the generated subnetworks.
Nutrigenetics and nutrigenomics, which seek to identify genetic variation relevant to food's absorption, processing and effect in the body, is also absorbed with the molecular relation between food and DNA.
The experimentally obtained intrinsic viscosity versus molecular weight relations of the polystyrenes conform well to the Mark-Houwink-Sakurada (MHS) equation and the Dondos-Benoit (DB) equation in the molecular-weight ranges considered.
The approach combines statistical techniques to identify candidate papers containing relevant evidence, followed by use of Textpresso and Hidden Markov Models (HMMs) to identify sentences and terms containing the desired molecular function relations for presentation to biocurators.
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