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Other up-regulated genes encode molecular regulators of energy metabolism.
PHDs (mainly PHD-2) were shown to represent the molecular regulators of HIF-1 activity regulating ubiquitination and subsequent proteasomal degradation of the HIF-1α subunit [26] [28].
Given these observations, it is not unreasonable to expect that the molecular regulators of these developmental changes might also regulate brca1 expression.
A number of key genetic and molecular regulators of yield component traits, especially seed size and number, have been identified.
Significant effort was dedicated to identifying the molecular regulators of these processes and the developmental defects resulting from gene modifications.
In addition, the expression of SOC1 and SUPERMAN, molecular regulators of flowering, was suppressed in the MYB62 overexpressing plants.
In this article, we review some of the recently identified molecular regulators of connexin assembly, membrane targeting, and degradation, focusing on the role of post-translational phosphorylation of connexin 43, the major gap junctional protein expressed in ventricular myocardium.
Complex interactions have been reported between molecular regulators of endothelial function [12].
Despite recent confluence of discoveries on brown fat adipogenesis, molecular regulators of this complex mechanism are not fully identified.
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Collectively, these results support our hypothesis that Ang1 is a key molecular regulator of pathological vascularization characteristic of malignant astrocytomas.
Here we discuss an important molecular regulator of cell death, DAP-kinase (DAPk), which presents a promising target for therapeutic intervention.
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