Sentence examples for molecular recognition that from inspiring English sources

The growing number of crystal structures of these 'alternative' scaffold-based binding proteins in complex with their targets illustrate the mechanisms of molecular recognition that are common among these systems and those unique to each.

This context has several aspects –subcellular localization or expression patterns will determine whether proteins that are potential competitors for an interaction in vitro actually meet in vivo and thus evolve into niches of molecular recognition that allow them to bind only the desired target domain.

The development of mAbs, led by Kohler and Milstein in the 1970s, has eliminated the variability in molecular recognition that plagued analyses using pAbs.

A novel strategy for enhanced molecular recognition that utilized standard complexation strategies in combination with light-induced, or photo-, polymerization was recently demonstrated.

Correct charging requires accurate molecular recognition that distinguishes one tRNA from another.

The presence of disorder in human SIRT1 and the propensity of these proteins in promoting molecular interactions make it important to understand the underlying mechanisms of molecular recognition that reasonably should involve terminal segments.

It is recognized that crystallization is associated with molecular recognition events that lead to self-assembly, and that pharmaceutical function and thermodynamic stability can be altered with a slight change in the interacting molecules or their molecular network motifs.

Proximity ligation assay (PLA) is a molecular recognition assay that depends on the ligation of two oligonucleotide-tagged probes that are capable of forming a complex, when binding to a target (or targets) that are in close proximity to each other [ 12, 13].

As part of our effort to define molecular recognition networks that lead to signalling, we investigated the effect of JAB on both JAK2 phosphorylation and JAK2 interaction state that ensue upon IL-5 stimulation in recombinant 293T cells cotransfected 293T cells with IL-5Rα, βc and hJAK2 either with or without JAB.

Optical fibers are often used as the integrating medium, linking the components of an optoelectronic instrumentation with a molecular recognition element that generates a response in the presence of the analyte.

MUC1 aptamer was a molecular recognition probe that led the internalization of two nano-complexes into MDA-MB-231 and MCF-7 cells (MUC1 positive cells) but not into HepG2 cell (liver cancer cell line, MUC1 negative cells).