Sentence examples for molecular recognition studies from inspiring English sources

Exact(3)

In the future, these molecular recognition studies may help in the development of new drugs capable to block bacterial adhesion.

In the presence of excess hydrogen bond donors and acceptors, the oligoanthranilamide strand retained its linear conformation, pointing to the potential of this modular design as a useful and stable scaffold for molecular recognition studies.

Urotropine is a convenient molecular scaffold in the formation of linear to macrocyclic supramolecular assembly with designed phenolic substrates based on both conventional O H⋯N and unconventional C H⋯O hydrogen bonds in molecular recognition studies.

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Thus, to clarify important subtleties of molecular recognition, we studied the effects of replacing a single pyrrole with β-alanine in 8-ring polyamides designed against the Ets-1 transcription factor.

Natively disordered or unstructured regions are found to be associated with molecular assembly, protein translation, modification and molecular recognition [ 33- 35].Previoustudieses indicate that disordered regions are strongly correlated with local solvent accessibility areas [ 36- 38].

As a complement, we present novel experimental results on the development and proof-of-concept application of a combinatorial approach to study molecular recognition in CA and its inhibition by peptide compounds.

In this chapter we will describe the most important NMR techniques developed to study molecular recognition processes involving proteins and nucleic acids also focusing on their application to drug discovery and development.

Although phage display traditionally is focused more on development of medical preparations and studying molecular recognition in biological systems, there are some examples of its successful use for detection, which are presented in the review.

For two recently studied molecular recognition events, experimental evidence has been provided for the latter mechanism [ 8, 9].

Michael Sattler (European Molecular Biology Laboratory, Heidelberg, Germany and GSF Research Center for Environment and Health) illustrated the power of modern NMR methods capable of producing well resolved three-dimensional structures of large biomolecules including description of dynamics and reactivity: NMR to study molecular recognition and dynamics of biomacromolecules.

The competition between halogen and hydrogen bonding in driving molecular recognition processes has been studied in crystal and biomolecular engineering, and in both cases it has been shown that it is possible for the former to outperform the latter under similar molecular environments.

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