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There is high structural homology within the pro-death and pro-survival families, yet a high degree of interaction specificity is nevertheless encoded, posing an interesting and important molecular recognition problem.
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A special peptide (CFYSHSFHENWPS) was used as molecular recognition probe.
Although the accurate prediction of binding free energies remains an unsolved problem, the current level of understanding of molecular recognition is such that computational methods can be extremely useful in the design and interpretation of experimental results.
This property allows the quantification of the predictive performance of virtual screening methods on a fraction of a given molecular dataset and makes the predictiveness curve an efficient tool to address the early recognition problem.
Overcoming resistance problems requires first and foremost an integrated and systematic understanding of the structural determinants and molecular recognition processes involving the drug and its cellular targets.
Molecular Recognition.
Mann, S. Molecular recognition in biomineralization.
Separation, molecular recognition, and reactive surfaces.
CHEM G8314 Molecular Recognition and Self-Assembly.
It is all a matter of affinity, molecular recognition and genetic programming, Dr. Belcher said.
The molecular recognition mechanisms were investigated.
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