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Aptamers are good molecular recognition elements for biosensors.
Thus, their findings show that nanopipettes functionalized with appropriate molecular recognition elements can be used as nanosensors in biomedical and biological research.
The antitoxin EcPaaA2 is characterized by two α-helices (H1 and H2) that serve as molecular recognition elements to wrap itself around EcParE2.
The chemical assemblies include conjugated PDA, responsible for the chromatic transitions, and the molecular recognition elements, which are either chemically or physically associated with the PDAs.
This aptasensor design opens up a new sensing mode, which is promising for rapid development of SELEX generated molecular recognition elements.
If recent scientific progress is a fair indicator, the future promises remarkable new developments in molecular recognition elements for use in biosensors with a vast array of applications.
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The optical fiber chemical sensor consists of the following basic components: (1) an optical fiber, (2) optoelectronic instrumentation, and (3) a solid-phase molecular recognition element.
This method has combined the exceptional quenching capability of GO and an aptamer with high specificity and affinity employed as the molecular recognition element.
Owing to these indispensable advantages, aptamers have been implemented as molecular recognition element as alternative to antibodies in various assays for diagnostics.
A specific biotin-labeled peptide (biotin-GPLGVRGKGGC, P1) acted as a molecular recognition element was firstly anchored on the Au nanoparticles modified electrode surface.
The ECL biosensor employs an aptamer as a molecular recognition element, and quenches ECL of tris(2,2′-bipyridine) ruthenium (Ru bpy 32+) by ferrocenemonocarboxylic acid (FcA).
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