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We propose that an active lifestyle is an important determinant of quality of life and molecular progression of aging in skeletal muscle of the elderly, and is a viable therapy for attenuating and/or reversing skeletal muscle strength declines and mitochondrial abnormalities associated with aging.
This would allow for better understanding of how molecular progression of the disease occurs.
Genetically engineered small animal models can be used to study the molecular progression of cancer that develops spontaneously over time [ 7].
We developed a mouse model mimicking human BRCA1-deficient breast cancer to gain insight into the molecular progression of BRCA1-deficient tumors and to test putative therapies [ 12].
The cataract can be easily detected and tracked by noninvasive and highly sensitive optical techniques, so the lens would provide an ideal "window" to monitor the molecular progression of AD.
Retrospective lineage analysis supports the distinct origins of segments of the heart from individual precursor pools (Meilhac et al., 2003; Buckingham et al., 2005; Meilhac et al., 2004b), but several questions remain regarding the timing and molecular progression of cardiac specification (Meilhac et al., 2004b).
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The identification of cancer-associated long non-coding RNAs and the investigation of their molecular and biological functions are important for understanding the molecular biology and progression of cancer.
Elucidation of genetic alterations is an approach to understanding the underlying molecular mechanisms of progression of human prostate cancers.
Complex interactions of biological knowledge might reflect the complex molecular pathogenesis and progression of ovarian cancer.
There is active ongoing research in the field of molecular pathogenesis and progression of MBL to CLL.
It is therefore urgent to understand the molecular mechanisms of progression of invasive bladder tumours, in order to develop alternative therapies to BCG.
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