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We propose that an active lifestyle is an important determinant of quality of life and molecular progression of aging in skeletal muscle of the elderly, and is a viable therapy for attenuating and/or reversing skeletal muscle strength declines and mitochondrial abnormalities associated with aging.
This would allow for better understanding of how molecular progression of the disease occurs.
These observations suggest that PIM kinases represent molecular progression markers rather than primary therapeutic targets in DLBCL.
Genetically engineered small animal models can be used to study the molecular progression of cancer that develops spontaneously over time [ 7].
Molecular progression was defined as an at least 10-fold (1 log) increase in MRD in ASO RQ-PCR between consecutive bone marrow analyses.
We developed a mouse model mimicking human BRCA1-deficient breast cancer to gain insight into the molecular progression of BRCA1-deficient tumors and to test putative therapies [ 12].
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The new available therapy for glioblastoma is based on better understanding of molecular malignant progression in this tumor.
These results suggest that miRNAs play an important role in molecular pathogenesis, progression and prognosis of GBMs.
Similarly, complex interactions of genes, TEX264, SFXN3, CD2AP, GPR64, and ABR, might act on crucial role in molecular pathogenesis, progression, and prognosis of ovarian cancer through the expression.
Therefore, at a molecular level, progression to failure is primarily a function of ongoing parenchymal injury caused by various specific diseases like recurring glomerulonephritis or ABMR.
These include molecular epidemiology, cancer progression and intervention, cancer treatment and service delivery, drug development and experimental therapeutics, and cancer genetics and molecular diagnostics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com