Sentence examples for molecular profiling it from inspiring English sources

Although PM has been boosted by the huge developments in molecular profiling, it is clear that nowadays imaging can provide comparable information.

When putative prognostic or predictive genes are proposed by molecular profiling, it may be desirable to compare gene expression with expression of downstream proteins.

According to molecular profiling, it is assumed that the luminal subtype arises from cells belonging to the luminal lineage, whilst the basal subtype is supposed to derive from less differentiated cells of the gland - such as stem/progenitor cells - that are normally located within the basal/myoepithelial compartment and exhibit basal phenotypic markers.

Given the efficacy of aflibercept in treatment-naive eyes and its specific molecular profile, it is possible that improved outcomes may also be achievable in patients with refractory neovascular AMD previously treated with bevacizumab or ranibizumab.

Given the complex interactions between outcome and distinct molecular profiles, it is obvious that the prognostic significance of S-CRC can be safely assessed only through the analysis of single molecular subgroups of CRC.

From the molecular profile, it is known that multiple copies of potential Sp-1 binding sites are clustered upstream of the start site for the initiation of TP transcription (Zhu et al, 2002).

Drug companies are intensely interested in ways of predicting which patients are likely to respond to chemotherapy, and there is some evidence that p53-and molecular profiling like it-may help identify patients likelier to respond.

First, although some genetic changes in IBC are shared with other forms of breast cancer, for the most part it is as distinct in its molecular profile as it is in its phenotype.

Furthermore, OC lacks a clear molecular profile making it difficult to elucidate a universal cause in OC initiation or progression [ 41– 41].

The clinical information required was determined by the aim of the molecular profiling study and it includes survival data, such as date and cause of death, treatment information, such as chemotherapy, surgery and radiotherapy type and bio-marker information such as ER, PR and HER2 status.

The tumour morphology reflects the molecular profile that produced it and consequently each can be predictive of the other.