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Moreover, the overlap between molecular profiles observed in neural development and adult regeneration suggests that a significant recapitulation of neurogenic programs is present in the course of regeneration.
Thus, to better understand the possible effect of gene conversion on the molecular profiles observed for HLA genes, we tested for the presence of significant conversion fragments within HLA sequence alignments using the GENECONV program [83], [84] (Table 4).
With the different molecular classifications of breast cancer now firmly established, researchers have turned their attention to breast cancer cell lines to determine whether the molecular profiles observed in breast carcinomas are reflected in cell line models of the disease.
The presence in unaffected and malign respiratory tract epithelia of principal amphiphilic AChE dimers (G2A), most likely consisting of GPI-linked AChE (Fig. 4), agreed with the molecular profiles observed in studies of unaffected and cancerous breast and other epithelial tissues [ 8, 25, 54].
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Thus, the inoculation of cattle with a pool of scrapie isolates of possibly various strains may have contributed to the heterogeneity in the molecular PrPres profiles observed in this study.
This demonstrates that although MVD status is associated with the tumor vascular clusters identified here, additional properties of the samples are primarily responsible for the molecular profiles and observed clustering.
To improve our understanding of the molecular basis for mutagenic profiles observed following exposure to the genotoxic agent MDA, we have studied the in vitro catalytic properties of the model Y-family DNA polymerase Dpo4 from S. solfataricus opposite M1dG.
This study presents a powerful approach to unveil the molecular basis for various complex phenotypic profiles observed in gene deletion experiments.
It is clear that more molecular studies are needed to probe the role of RdDM in contributing to the contrasting genomic profiles observed across land plants.
Future research on the cnidarian molecular clock should focus on the protein interactions within this system and how they produce the novel clock gene expression profiles observed in this work.
The main hypothesis is that a differential molecular profile can be observed depending on the stressor's origin, with correlations evoking cross-regulation, and that the related initial blood profile can predict the diagnosis of sepsis.
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