Sentence examples for molecular profile based from inspiring English sources

The molecular genotype of the isolates from both leg and brain biopsies show that the molecular profile based on multilocus sequence (MLS) analysis of both coding (MLST) and more variable noncoding (VNTR) markers is shared with only two clinical isolates (one from Australia, and the other from an organ transplant recipient in San Francisco, California) out of 85 VGI strains typed [10], [32].

Recent evidence suggests that histologically similar lung tumors harbor distinct molecular profiles based on smoking status, and that these alterations underlie observed clinical disparities between lung tumors in smokers and NS [ 3].

It has been shown that breast cancer is a very heterogeneous disease with four different molecular profiles based on the expression pattern of ERBB2, estrogen and progesterone receptors, and histological grade.

In extension to the latter threshold based code, a non threshold based real time molecular profiling, based on mathematical theorems [19, 20], enables the investigator to directly visualise large multimolecular assemblies, e.g., associated with the basal lamina (Fig. 1a), or detect protein profiles that sharply distinguish between normal and diseased tissue at the same time [4] (Fig. 2).

The gene expression signature of post-septic BMDC provided a molecular and functional profile based in GEO.

We also consider methods for improvement of molecular profile-based prediction of response to primary chemotherapy by classification of samples according to cellular makeup or by the incorporation of sample tumour content information into the predictor.

Age-related differences in GBM tumors and HGGs are evident when considering molecular profiling studies based on global gene expression and copy number analysis [ 44, 51, 52].

As a comprehensive molecular approach, gene expression profiling based on cDNA microarray is reportedly advantageous for discriminating between N0 and N+ patients, with clustering analysis of at least 100 to >1,500 metastasis-associated genes being employed [ 80, 81].

Here only the genotypic information was used to retrace geo-location associations of similar genetic profiles based on 20 microsatellites molecular markers (SSR) [37, 46].

While neuroanatomical methods enable high-resolution mapping of neural circuitry, these approaches do not allow systematic molecular profiling of neurons based on their connectivity.

Molecular profiles were constructed based on the selected cell line's ability to express various markers of transformation (c-Neu, cyclinD1, p21, p27 waf)), cell status (VEGF, IGF-R, c-Met, CK19), invasiveness (MMPs -12 and -13) and inflammation (NFκB).