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The down-regulation of ALCAM in our series of USC samples reinforces its potential role as a molecular predictor of invasiveness and poor outcome in endometrial cancer patients.
In addition, MALAT1 may serve as a molecular predictor of early progression.
If these results will be confirmed, MR4.5 will represent a new molecular predictor of long-term outcome.
Therefore, this meta-analysis supports the outcomes of many studies which found that MALAT1 is a molecular predictor of OS.
Despite a suggestion of a predictive role of PI3K pathway inactivation by the latter two studies, no convincing molecular predictor of EGFR TKIs efficacy have emerged.
This study represents the first true external validation of a molecular predictor of response to cetuximab in KRAS-WT metastatic CRC.
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For penile cancer (PC) there are no known molecular predictors of lymphatic spread and/or chemoresistance.
We identified 422 reported genetic and molecular predictors, of which 52 had ⩾2 studies.
This study analyses reported genetic and molecular predictors of prognosis in GBM.
Potentially, translational research has power in the identification of molecular predictors of activity leading to stratification in clinical studies and eventually to individualised therapy.
An attraction of molecular predictors of genetic risk compared to pedigree predictors is the potential to apply the predictions more widely within populations and across populations.
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