Sentence examples for molecular platforms that from inspiring English sources

Such polyQ aggregates form molecular platforms that affect the solubility of protein partners and influence interactions 19.

They are also known to function as molecular platforms that organize appropriate molecules for specific signaling pathways [ 5]. uPAR, a glycosylphosphatidylinositol-anchored membrane protein with multiple functions in extracellular proteolysis, cell adhesion, cell migration and cell proliferation, is found in both the lipid rafts and in more fluid regions of the plasma membrane [ 6].

Many scientists argue that the molecular platforms that sail on the cell's outer, or plasma, membrane, known as lipid rafts, either don't exist or have no biological relevance, but their supporters insist the idea remains afloat.

Many scientists argue that the molecular platforms that sail on the cell's outer membrane, known as lipid rafts, either don't exist or have no biological relevance, but their supporters insist the idea remains afloat.

The inflammasome is a molecular platform that regulates the activation of caspase-1, which leads to the cleavage of interleukin-1 β (IL-1 β).

Hence, SLP-65 provides a molecular platform that links BCR engagement to the regulation of important transcription factors and the reorganization of the cytoskeleton.

This role of the polyribosome as a molecular platform that is actively involved in the ordered translation of protein complexes may provide new avenues toward the understanding of the implication of protein aggregation in a vast number of pathologies such as Alzheimer's disease.

39, 40 In addition, the NF-κB pathway has been shown to activate the NLRP3 inflammasome, a multi-protein, cytosolic molecular platform that controls the activation of caspase 1, and the secretion of proinflammatory cytokines interleukin IL-1β and IL-18 in metabolic stress.

This bottom-up approach results in a molecular platform that mimics biological systems with potential for encapsulating and delivering drug molecules.

The conformational organization may be advantageous in the formation of a molecular platform that assembles multiple proteins.

We anticipate that these ongoing efforts will prove to be valuable both as enabling tools for accelerating our understanding of microenvironmental regulation in GBM and as foundations for next-generation molecular screening platforms that may serve as a conceptual bridge between traditional reductionist systems and animal or clinical studies.