Sentence examples for molecular phenotypes such from inspiring English sources

A crucial first step in this process is to understand how polymorphisms alter molecular phenotypes, such as protein-coding gene location, structure, and expression pattern.

More recently, a number of groups have shown how integration of intermediate molecular phenotypes, such as gene and protein expression levels, can be used to aid the reconstruction of these pathways and genes [2] [6].

Alternatively, molecular phenotypes such as gene expressions are considered.

Comparison of the two studies also highlights the shared relevance of certain cellular and molecular phenotypes, such as cell death and mitochondrial dysfunction.

Also the integration of molecular phenotypes, such as gene and protein expression levels in combination with eQTL, can be used to aid the reconstruction of these pathways and genes (Fu et al. 2009; Terpstra et al. 2010).

It is possible that distinct subgroups of asthmatics exist with specific shifts in PPAR/TLR pathways that correlate with GC responsiveness or other molecular phenotypes, such as the IL-13 related Th2 sub-phenotypes previously described for the current data set [ 47, 48].

These results draw attention again to a paradox that have recently been generated by a number of conflicting observations from other laboratories working with various diagnostic means to characterize molecular phenotype, such as screens of TRPV1+ in various cells and tissue types.

The connection between an altered molecular phenotype such as that observed in M5 and the development of pathological hypertrophy remain unknown.

In recent years, the term 'phenotype' has been applied broadly to include any cell property, including 'molecular phenotypes' such as the mRNA level of a single gene.

The diversity of possible molecular phenotypes makes such aberrant splicing challenging to corroborate at the scale required for complete genome (or exome) analyses.

Second, molecular prognostic phenotypes such as germinal center (GC) and activated B cell were not included in this analysis because study protocol approved by IRBs of each center did not require mandatory tissue collection.