Sentence examples for molecular phenotypes on from inspiring English sources

Here we introduce an alternative strategy: a "synthetic association study" in which we computationally predict molecular phenotypes on artificial genomes containing randomly sampled combinations of polymorphic alleles, and perform a classical association study to identify genotypes underlying variation in these computationally predicted annotations.

Nonetheless, it is major limitation that the results of molecular phenotypes on this series of patients are not available.

Therefore, it was likely that the influence of molecular phenotypes on prognosis would quite be decreased in our cohort.

As in routine laboratory analysis, standards and ranges need to be defined to distinguish between different molecular phenotypes on an individual basis.

The maturity of gene expression microarrays relative to similar technologies designed to measure other molecular phenotypes on a genomic scale has meant that gene networks primarily are rendered as gene coexpression networks.

In this work, we classify phenotypes into two broad categories: (i) molecular phenotypes, an immediate effect of a specific gene sequence, and (ii) cellular phenotypes, the influence of molecular phenotypes on various cell populations.

Recent studies have revealed that there are several molecular phenotypes of breast cancer, based on receptor expression [2].

The adult tumors evident between 1 3 months of age faithfully reproduce the immunological, histological and molecular phenotypes of human melanoma, but on a condensed time-line.

The molecular phenotype of HER2 expression on CD14+ monocytes has not been clearly investigated and, as such, our understanding of the extent and clinical significance of this trogocytosis is still very limited [ 9- 14].

However, we can look forward to a future in which we will perform molecular phenotyping of resistant tumours on an individual basis and devise novel rational circumventing treatments using that knowledge.

This technique is well suited to high-throughput whole genome detection of chromosomal gains and losses at high resolution, enabling rapid detection of homozygous loss, which allow molecular phenotyping of tumours based on the underlying abnormalities and the detection of amplicons, which may be associated with overexpression of oncogenes.