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Martins, D. et al. Molecular phenotypes of matched in situ and invasive components of breast carcinomas.
Wei, X. et al. A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.
Using computational approaches to Integrate clinical, biological, genomic and proteomic data to identify new molecular phenotypes of disease.
We have developed a highly parallel strategy, systematic gene-to-phenotype arrays (SGPAs), to comprehensively map the genetic landscape driving molecular phenotypes of interest.
Bred to a Ptbp2 knockout, the transgene allowed us to compare the developmental and molecular phenotypes of mice expressing only PTBP1, only PTBP2, or neither protein in the brain.
The cellular and molecular phenotypes of reduced RNASEH2C level were next investigated.
Recent studies have revealed that there are several molecular phenotypes of breast cancer, based on receptor expression [2].
If validated, syndecan-1 might be useful as a biomarker to help further distinguish molecular phenotypes of ARDS.
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Li, Y. et al. Excision of expanded gaa repeats alleviates the molecular phenotype of Friedreich's ataxia.
Suslov, O. N., Kukekov, V. G., Ignatova, T. N. & Steindler, D. A. Neural stem cell heterogeneity demonstrated by molecular phenotyping of clonal neurospheres.
Moreover, mass spectrometric analysis of the intact proteins can contribute towards molecular phenotyping of MUPs.
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