Only CRTAC1 expression correlated with 2D/3D switches while the molecular phenotype of native chondrocytes was not restored.
To investigate molecular phenotype of TNSALP (A116T), we expressed it in the COS-1 cells or Tet-On CHO K1 cells.
Because the HCS-2/8 cells are the most widely used cell line in cartilage research, we investigated the molecular phenotype of these cells by mRNA-expression profiling.
To develop a rapid biomarker method for confirming that leiomyoma and myometrium primary cultures maintain the molecular phenotype of the progenitor tissues.
This article reviews the histological features, the endoscopic appearance, the natural history and the molecular phenotype of the different categories of serrated polyps and introduces the concept of "serrated neoplastic pathway" in the development of colorectal cancer.
Using gene expression and proteomic profiling, it has been possible to explore the molecular phenotype of the human retinal endothelial cell and contribute to understanding of the pathogenesis of these diseases.
We then examined the molecular phenotype of type-3 cells, a cell type that transiently expresses Calretinin [26].
In this study, we show that they at least share a common molecular phenotype of sustained nuclear FOXO3a expression.
We chose neoplastic samples for this purpose because of the previously suggested similarities between the molecular phenotype of placental tissues and tumors [25].
The fact that some of these genes are aberrantly methylated at the DNA level in a variety of tumors[37] is notable given the previously noted link between the "molecular phenotype" of tumors and early mammalian development[25].
Using these reporters to assess the molecular phenotype of the FOXL2-C134W mutant is relevant, because their promoters have been previously shown to display various affinity levels and specific behaviors towards distinct types of FOXL2 mutations [23], [25], [27], [28].
