Sentence examples for molecular pattern molecule from inspiring English sources

We elucidated the mechanism by which the nuclear-damage-associated molecular pattern molecule, high-mobility group box 1 (HMGB1) was released from the impaired hepatocytes and induced endoplasmic reticulum stress to activate HSCs.

High mobility group box 1 (HMGB1) is an abundant protein that regulates chromosome architecture and also functions as a damage-associated molecular pattern molecule.

HMGB2 is a member of the HMG box family and acts as a damage-associated molecular pattern molecule.

HMGB-1 functions as an alarmin or damage-associated molecular pattern molecule, and acts as an endogenous ligand for pattern recognition receptors of the innate immune system.

S100A12 is released by activated neutrophils or by damaged cells under stress as a damage-associated molecular pattern molecule (DAMP) [ 3].

Furthermore, HMGB1 can be released from both activated and dying cells thereby acting as a damage-associated molecular pattern molecule [ 195].

ELISA showed that cPcAMP1 and cPcAMP1/26 were able to bind to microbe-associated molecular pattern molecules LPS and LTA, which was further corroborated by the observations that cPcAMP1 could deposit onto the bacterial membranes.

DAMPs damage-associated molecular pattern molecules; TLR toll-like receptor.

These immune responses are triggered following recognition of common microbe-associated molecular pattern molecules (MAMPS) or pathogen-associated molecular pattern molecules (He et al. 2007; Bent and Mackey 2007).

Volume I of the book describes the network of damage-associated molecular pattern molecules (DAMPs) and examines the central role of DAMPs in cellular stress responses and associated regulated cell death, the promotion and resolution of inflammation, the activation of innate lymphoid cells and unconventional T cells, the stimulation of adaptive immunity, and tissue repair.

The migration of cancer cells may also be affected by certain hormones (e.g., follicle-stimulating hormone, FSH; luteinizing hormone, LH), cleavage fragments of the complement cascade (C3 and C5 cleavage fragments; C3a and C5a, respectively), components of the coagulation cascade (e.g., thrombin), and certain danger-associated molecular pattern molecules (DAMPs; e.g., S100 proteins) [11 16].