Sentence examples for molecular pathways we from inspiring English sources

Because Lodamin can target broader molecular pathways, we expect it will improve therapeutic outcomes compared to VEGF blockers.

To elucidate the effects of Fkbp5-deletion on molecular pathways, we compared the expression profile of Fkbp5 +/+ and Fkbp5 −/− litter mates.

To investigate the association between EBV-infected B-cell lymphoma cells and molecular pathways, we then conducted in vitro functional analysis.

To explore the NCL-associated disease pathology and molecular pathways, we have previously produced targeted knock-out mice for Cln1 and Cln5.

Considering the general notion that cancer metastasis is a result of multifactorial crosstalk between different molecular pathways, we generated significant functional association networks in invasive cells (see Additional file 4).

In light of the ability of the CREB pathway to influence transcription of other genes and molecular pathways, we evaluated differences in genome-wide expression in OVCAs that demonstrate high vs low CREB pathway expression.

To test the hypothesis that col27a1a compensates for knockdown of col27a1b, and to determine if these loci function in the same molecular pathway, we injected zebrafish embryos simultaneously with col27a1a and col27a1b TBMOs at dosages (1 ng) that did not individually cause morphological defects.

Independent of the precise molecular pathway, we assume that (pro-) endocrine factors X and Z independently suppress the expression of Y leading to the restriction of the latter factor to the exocrine compartment.

By molecular pathway analysis, we identified the pathways termed "Neuroactive ligand-receptor interaction", "Wnt signaling pathway", "CREB signaling in neurons", and "Axonal guidance signaling", all of which are closely related to neuronal functions, as the pathways relevant to NRSF target genes in ESC.

Here, we review recent genetic and genomic findings in studies of PD, we provide some integration and synthesis of the molecular pathways involved, and we discuss the translational implications.

Consistent with a molecular link between pathways, we found that BCR-NOTC Hactivation significantly increased the proximal BCR adapter protein BLNK.