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Characterizing the relationship between the modern environment and the human molecular pathways underpinning its impact on early development is paramount to understanding the public health significance of modern day chemical exposures.
It may indicate common molecular pathways underpinning both aspects of SWD.
Through comparative analyses we identified molecular pathways underpinning this response, including the insulin signaling pathway.
Dopamine is thought to be involved in the molecular pathways underpinning positive symptoms, including hallucinations and delusions.
These data provide insights into the molecular pathways underpinning axonal and synaptic vulnerability in the NCLs and also identify potential biomarkers of early neuronal vulnerability in NCL pathology.
This analysis was designed to reveal any significant convergence or divergence in the molecular pathways underpinning early changes in synaptic and axonal vulnerability in the NCLs.
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The precise molecular pathway underpinning the licensing checkpoint is currently unclear, but appears to involve p53 and converges on down-regulating G1/S Cdk2 activity.
In addition to epigenetic regulation, alternative splicing represents the second molecular process in which a structurally diverse set of NC-RNAs interact to generate spatial and temporal complexity in cellular signaling pathways, underpinning phenotypic plasticity.
Signalling pathways underpinning RSA responses to individual nutrients, particularly nitrate and phosphate, have been unravelled.
Such a task requires comprehensive systems-level understanding of the enzymatic and regulatory pathways underpinning this temporal CO2 pump.
Dysregulation of pathways underpinning each of these processes has been implicated in neoplastic transformation of various tissue types.
More suggestions(10)
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