Sentence examples for molecular pathways potentially from inspiring English sources

In order to identify molecular pathways potentially altered by the expression of multiple miRNAs, we used the DIANA-mirPath web-based computational tool [ 37], free available at [ 38].

This allowed identification of molecular pathways potentially altered by the expression of single or multiple miRNAs (http://diana.imis.athena-innovation.gr/DianaTools/index.php?r=mirpath/index) [ 21].

The DIANA-mirPath web-based computational tool [ 13] was used to identify molecular pathways potentially altered by the intersection of miRNAs differentially expressed in fractured bone.

To identify molecular pathways potentially involved in observed cellular effects, we performed a gene microarray analysis of 3T3 Dohhflox/flox; Crepos.

The key molecular pathways potentially altered by the miRNAs differentially expressed in normal and OA chondrocyte micropellets, as predicted by the DIANA-mirPath web-based computational tool, include TGF-beta, Wnt, MAPK and mTOR signalling, focal adhesion and regulation of actin cytoskeleton among others.

In silico analyses predicted that key molecular pathways potentially altered by the miRNAs differentially expressed in normal and OA chondrocytes include TGF-beta, Wnt, Erb and mTOR signalling; all of them implicated in the development, maintenance and destruction of articular cartilage.

Further, we carried out phosphokinase array analysis to investigate molecular pathways that potentially contribute to ouabain-mediated cell death.

Notably, this method also means that each miRNA can modulate several molecular pathways with potentially unpredictable side effects.

Then, if more experience can be gathered on molecular pathways that potentially qualify for explaining observed epistasis effects, they could be generalized into a collection of semantic motifs.

Combining unsupervised, pathway-level and transcript-level analyses, we identified tissue- and population-specific transcripts, as well as whole molecular pathways that potentially control the biological functions of APCs in the human vaginal mucosa and the skin [ 3, 5, 44].

Any genetic difference in individuals that could modulate the defined molecular pathways could potentially influence susceptibility to EAE and MS. The eQTL approach can facilitate identification of candidate genes (6, 14, 15) and in the current study our whole-genome approach identified genetic differences between two inbred rat strains that contribute to the expression of individual genes.