Sentence examples for molecular pathways mediate from inspiring English sources

To determine whether common molecular pathways mediate such shared HSC responses during differentiation, mobilization, and leukemic transformation, we next performed a meta-analysis of the differentially regulated genes from these three pairwise comparisons.

This observation suggests that IRF4 controls an aspect of Treg biology that is essential for moderating the GC itself and that specific, cell-intrinsic molecular pathways mediate the suppression of the spontaneous GC response by Treg cells.

Distinct molecular pathways mediate the dual role of the hypoblast: FGF, which controls the Wnt-PCP pathway and positions the PS (Voiculescu et al., 2007), and Nodal antagonism (perhaps together with Wnt antagonism), which regulates the timing of PS formation (Bertocchini and Stern, 2002).

Over two decades ago the discovery of microRNAs (miRNA) broadened our understanding of the diverse molecular pathways mediating post-transcriptional control over gene expression.

Because little is known about the biology and genetics of the metastatic process, we desired to elucidate molecular pathways mediating pancreatic cancer metastasis in vivo by an unbiased forward genetic approach.

However, the endogenous molecular pathways mediating these actions are poorly understood.

Accordingly, studies to dissect the molecular pathways mediating ES/iPS cell differentiation into the cardiomyocyte lineage are essential.

However, molecular pathways mediating effects of glucocorticoid overexposure on motor and cognitive development are poorly understood.

Future studies are needed to further define the additional molecular pathways mediated by miR-199a-3p miR-199a-3p miR-199a-3p

Elucidation of the molecular pathways mediating stem cell SCS expression is a crucial step towards improving our understanding of the secreted factor profile and its clinical utility [ 204].

The molecular pathways mediating the toxicity of TCDD are also likely to be more extensive than the impairment of AP-1 signaling.