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It is important to note in any discussion of research on the role of monocytes and macrophages in the initiation and persistence of tissue fibrosis in human disease that the majority of investigations employ animal models, most commonly mice to identify the molecular pathways important in the regulation of this process.
Called everolimus, this new pill targets molecular pathways important for cancer cell growth, division, and survival.
Osteosarcoma is the most common primary malignancy of bone with poorly characterized molecular pathways important in its pathogenesis.
Of these 450 E-dependent DEG, 291 were up regulated (within a range of 2 to 47-fold change), and 159 DEG were down regulated (range between −2 to −15.7-fold change) in the absence of E. We hypothesised that some of the E-dependent DEG would be involved in downstream molecular pathways important for maintaining the female gonad.
Where does SALL2 fit within the molecular pathways important for fissure closure?
The design of the newly established newt EST database allows identification of molecular pathways important for heart regeneration.
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The researchers determined that HARE5 likely controls a gene called Frizzled 8, which is part of a molecular pathway important in brain development.
To be pathogenic, a CNV must affect a gene in a molecular pathway important in the development or maintenance of the human body.
Functional annotation of the human airway basal cell signature points to molecular pathways likely important for known and potentially novel aspects of basal cell biology.
Data on epigenetic changes and other 'omics' level alterations with potential significance for critical pro-aging molecular pathways are important to collect.
Several molecular pathways are important for the development and progression of cutaneous melanoma (Herlyn et al, 2000; Bennett and Medrano, 2002) (Keller-Melchior-98, Pavey-02), and we have previously reported that both tumour cell proliferation and angiogenesis are increased in aggressive tumour subgroups (Straume et al, 2000; Straume and Akslen, 2001).
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molecular alterations important
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molecular markers important
molecular chaperones important
molecular determinants important
molecular pathways responsible
molecular mediators important
molecular targets important
molecular motors important
molecular scaffolds important
molecular events important
molecular factors important
molecular aspects important
molecular features important
molecular interactions important
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