Sentence examples for molecular pathways i from inspiring English sources

We have recently added an additional hallmark to these molecular pathways, i.e., dysregulation of the ECM, and dissected the distinct aging hallmarks for their differential contribution to the development of age-related chronic lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer, and idiopathic pulmonary fibrosis (IPF) [12].

Our data analysis focused on identifying significantly regulated biological processes and molecular pathways (i.e., gene functional analysis) instead of testing the differential expression of individual genes.

Ovarian cancer has been proposed to evolve through two distinct molecular pathways: type I low-grade pathway tumours have a 5-year survival of 55% and have frequently activating mutations of BRAF or KRAS, whereas type II high-grade pathway tumours with a 5-year survival of only 30% are characterised by inactivating mutations of p53.

Via FAIME, three independent prostate gene expression arrays with both normal and tumor samples were transformed into two distinct types of molecular pathway mechanisms: (i) the curated Gene Ontology (GO) and (ii) dynamic expression activity networks of cancer (Cancer Modules).

"I liked that Christensen outlined clear molecular pathways that might be responsible for the patterns I and others have seen," says Taylor.

This Appendix provides the theoretical framework and the conditions upon which integrating an ensemble of molecular pathway models, { M i } (for i = 1 to D) yields the dynamically integrated solution O is possible.

We initially investigated in our models the status of molecular pathways implicated in the modulation of temozolomide sensitivity (i.e. DNA MMR and MGMT; Middlemas et al, 2000).

Some molecular pathways were differentially expressed between early and mature biofilm (i.e. Ribosome; Purine Metabolism; and Glycolysis).

Because of this difference — again, I'm not an expert here, so I'm not going to try to explain the molecular pathways — it's been hypothesized that when people eat foods made with high-fructose corn syrup they feel less full.

This overlap was observable at three levels: (i) individual genes; (ii) general functional categories of genes; and (iii) molecular pathways implicated in aging.

On the basis of this need I present contemporary approaches that should aid our quest to identify and understand molecular pathways of pathogenesis.