Sentence examples for molecular pathways capable from inspiring English sources

The observed consensus pathways of T cell development, including requirements for ZAP-70, LAT, SLP-76, and Vav1, appear to reflect the restriction by Cbl of an otherwise much broader set of molecular pathways capable of mediating T cell development.

However, one of the main causes of its limited application in cancer treatment is that most tumours are not dependent on a single molecular pathway and are capable of circumventing single-target inhibition through the development of several mechanisms of resistance.

We consider that one of the best approaches currently available to accomplish this task are protein-protein interactions (PPI), because they encompass the scaffold of molecular pathways and cellular processes, besides being capable of revealing the dynamic and interactive function of human proteins [ 13].

This review, with a main focus on the role of EMT in tumors, will summarize the basic molecular events underlying EMT including the signaling pathways capable of its induction as well as changes in EMT-associated protein expression and will very briefly touch the role of microRNAs in EMT.

Recent research efforts are focused on developing compounds that inhibit tumour cell metabolism and cellular bioenergetics or related molecular pathways that selectively starve tumour cells of essential nutrients capable of generating ATP (Pelicano et al, 2006; Dwarakanath and Jain, 2009; Cheng et al, 2012, 2013).

Inspection of various molecular pathways associated with ependymomas may establish the foundation for developing novel therapies capable of achieving significant clinical improvements with individualized regimens specifically designed for personalized treatment strategies.

The complexity and redundancy of molecular pathways of weight regulation seem to hinder the identification of safe 'entry points' that are still capable of generating substantial effects.

Disruptions in these molecular pathways can cause disease.

Scientists may never halt the process entirely: ageing is an opaque and complex mingle of molecular pathways.

If the diseases are similar in some molecular pathways, perhaps the heart attack drugs should be tested against muscular dystrophy.

Although the molecular pathways are not well understood, retinol causes new collagen to form in chronologically aged skin and in skin damaged by ultraviolet light.