Sentence examples for molecular pathways already from inspiring English sources

This analysis revealed several genes and molecular pathways already known to be involved in aging, thereby validating the screen.

By binding to adrenoceptors in various organs, NE and EPI may modulate various intracellular molecular pathways already implicated in cancer (see below).

NE and EPI may affect cancer by interacting with molecular pathways already implicated in abnormal cellular replication, such as the P38/MAPK pathway, or via oxidative stress.

One possibility is that by binding to adrenoceptors on the outside of cells of the body's organs, they activate intracellular molecular pathways already implicated in cancer.

The genetic basis of a significant proportion of CMDs is still unknown; further understanding of the molecular pathways already identified may help to find these missing gene loci and aid both diagnosis and the development of therapeutic strategies.

Moreover, we identified one of the possible mechanism(s) involved in this up-regulation, the activation of a DNA damage response, a molecular pathway already described to regulate the expression of NK cells activating ligands in several cellular models [ 12, 24, 64].

These molecular pathways have already been extensively investigated in these animal models of spinal cord degeneration [ 7- 14].

Chourrout, personal communication) and previous observations that in Ciona neither one of the two hedgehog-related genes seems to be expressed in notochord cells [ 67], begin to pinpoint the molecular pathways that are already present in the simple tunicate notochord, as opposed to vertebrate innovations.

Functional annotation of up- and down-regulated transcripts showed several biological processes and molecular pathways that have been already reported in previous proteomic and transcriptomic studies to be altered upon controlled administration of low dosage corticosteroids.

Given the enormity of molecular reactions in the context of pathways already described to date, it is clear that we need to initiate systematic efforts at developing comprehensive pathway resources.

In summary, our findings demonstrate that multiple molecular pathways that are characteristically dysregulated in HD are already altered in undifferentiated pluripotent cells and that the pathogenesis of HD might begin during the early stages of life.