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Our results provide novel molecular pathway regulating programmed necrosis in heart.
In addition, analyses of the networks of autophagy-related proteins revealed a canonical molecular pathway regulating the process of autophagy in yeast and mammals.
The close phenotypic resemblance of Nde1+/−Lis1+/− and Nde1−/− mutants suggested a dose-dependent genetic interaction of Nde1 with Lis1, and that the two genes function in a common molecular pathway regulating cerebral cortical development.
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Indeed, p66Shc-/ mice are protected from diet-induced obesity, suggesting that this molecular pathway regulates diet-associated fat development [ 17].
Expression microarrays are a powerful tool that could provide new information about the molecular pathways regulating common lung diseases.
This prediction has profoundly altered paradigms for cancer research, compelling investigators to prospectively isolate CSCs to characterize the molecular pathways regulating their behavior.
Altogether, these findings suggest that Arc/Arg3.1 effects on memory formation are not only manifested at the level of molecular pathways regulating synaptic plasticity, but also at the systems level.
Molecular pathways regulating rapid proliferation and persistence are fundamental for pathogens but are not elucidated fully in Toxoplasma gondii.
Thus, Calsyntenin might be a key component of conserved molecular pathways regulating different aspects of learning and memory in diverse species.
This creates a unique opportunity to characterize the transcriptional programs active at various phases of neural commitment and differentiation, from which it might be possible to predict the molecular pathways regulating these processes.
Our knock-in mice provide an opportunity to study the molecular pathways regulating the myriad aspects of VCP disease and thus, may aid in the development of novel strategies for treatments of diseases with similar pathogenesis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com