In the future, when we have a better understanding of the molecular pathology involved in the development of ovarian cancer, this may allow us to better diagnose and treat, and eventually prevent, ovarian cancer.
The prevalence of obesity is exponentially rising world-wide [ 1] and its enormous consequences for the quality of life and life expectancy have led to the need for a better understanding of the molecular pathology involved.
Overall, it is crucial to delineate how specific changes in DNA methylation patterns of subsets of genes relate to the molecular pathologies involved in breast cancer initiation, progression and metastasis.
AD has a complex pathology involving several molecular pathways, such as amyloid deposition, taupathy, oxidative damage, inflammation and metabolic changes.
Our observations provide new insights into the molecular pathology underpinning NF2 involving mutations in exons 2 and 3. Merlin, similar to ERM proteins, influences cytoskeleton dynamics, and when merlin is absent in SCs, dramatic alterations in the actin cytoskeleton are observed (Gonzalez-Agosti et al., 1996; Lallemand et al., 2009a).
It seems there is often a pathology involved.
Since in addition to cytogenetics I also love molecular genetics, I am currently working with the Director of the newly established Division of Genomic and Molecular Pathology on getting more actively involved in routine molecular testing within the division.
Individually, these studies have advanced our understanding of the molecular systems involved in the molecular pathology of autism and have formed the bases of ongoing work to build autism biomarkers.
Using this experimental approach our data suggest that alternative splicing of the TRAIL gene might be involved in the molecular pathology of gastric carcinomas.
In addition to characterizing the host response to H. parasuis infection in animals of differing susceptibility, this project aimed to identify the pathways involved in the molecular pathology associated with Glässer's disease.
