Sentence examples for molecular pathogenic from inspiring English sources

Until now, the underlying molecular pathogenic mechanisms responsible for dental agenesis are still largely unknown.

To investigate the molecular pathogenic mechanism of the mitochondrial mutations, cell hybrids (namely cybrids) of mtDNA-deficient cells and enucleated lymphoblastoid cells from patients are generated.

This finding confirmed that the decrease in protein stability is the main molecular pathogenic mechanism in PKU and the determinant for phenotypic outcome.

Current advances in molecular biology, together with the development of Biobanks as stable sources of biologic material, are enhancing the possibility of detecting genetic factors involved in the molecular pathogenic mechanisms of migraine, a complex neurological disorder classified as the seventh most disabling disease worldwide.

The molecular pathogenic clone of SIVmac239 [30] and its derived deglycosylated mutants used in this study are depicted in Fig. 1.

The loss of genomic stability and resulting gene alterations are key molecular pathogenic steps that occur early in tumorigenesis: they permit the acquisition of a sufficient number of alterations in tumor suppressor genes and oncogenes that transform cells and promote tumor progression.

The molecular and pathogenic aspects of their biology are grouped in terms of their genomic organization.

Future investigations focusing on this area are warranted to explore the underlying molecular and pathogenic mechanism.

Because many genes across the genome have methylation sites in their promoters [2], extensive hypomethylation in AD may provide an over-arching principle that accounts for significant aspects of the molecular and pathogenic complexity of the disorder.

In most cases, hepatotoxicity is an unpredictable side effect of AZA, whose molecular and pathogenic mechanisms remain unknown [ 5].

However, until recently little was known regarding the molecular and pathogenic mechanisms by which NO contributes to the formation of fragmented mitochondria.