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These data allow for comparison of the molecular pathogenesis between autoimmune diseases and lymphoid malignancies.
This comprehensive dataset allowed us to compare the features of molecular pathogenesis between adult and pediatric B-ALL and to identify signatures possibly related to the inferior outcome of adults to that of children.
Further, we postulate that kinome analysis could provide information regarding conserved mechanisms of molecular pathogenesis between humans and animals routinely used in models of human malignancies.
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Here we focus on recent advancements in understanding the molecular pathogenesis of CM and the variable presentations between children and adults.
The insights in the molecular pathogenesis of lipomatous tumors show a morphological overlap between ordinary lipomas and well-differentiated liposarcomas in 16/97 (16%) cases.
These studies provide a molecular foundation to understand the cellular and molecular pathogenesis of human SCA11, and help account for the link between ciliary dysfunction and neurodegenerative diseases.
Prostate cancer is an attractive target for chemoprevention because of its ubiquity, treatment-related morbidity, long latency between premalignant lesions and clinically evident cancer, and defined molecular pathogenesis.
To further understand the molecular pathogenesis of TB, several molecular studies have attempted to compare the expression profiles between healthy controls and active TB or LTBI patients.
Myelodysplastic syndromes: molecular pathogenesis and genomic changes.
However, their molecular pathogenesis remains elusive.
Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, New York, NY 10016, USA.
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