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To develop a novel molecular panel of markers to detect breast cancer (BC) disseminated malignant cells in ovarian tissue, and to improve the safety of ovarian tissue transplantation.
We identified a urine molecular panel of proteins responding differently to albuminuria development in our patients: CD59, AAT and TNA.
Within this broad molecular panel, CK20 and uroplakin are the best molecular markers to determine urothelial origin of MPC [ 19].
Similar to these studies, we examined the mutational load in cell populations using a diverse DNA molecular panel to assess genomic instability.
Hence, we sought to develop a molecular panel for prostate cancer progression by reasoning that molecular profiles might further improve current clinical models.
We found that applying a broad diagnostic molecular panel during the SARS outbreak enabled timely identification of agents of common respiratory viral infections in more than one third of patients with suspect or probable SARS.
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Her research interests include how standards should be applied to breast cancer diagnostics (such as HER2 testing), the utility of molecular panel-based testing in breast cancer, and identifying the most appropriate management of specific pathologic diagnoses.
Her research interests include how standards should be applied to breast cancer diagnostics (such as ER and HER2 testing), the utility of molecular panel-based testing in breast cancer, digital pathology applications and identifying the most appropriate management of specific pathologic diagnoses.
Molecular signatures of disease are presently resolved by static indices and molecular panels comprised of experimentally validated biomarkers that diagnose patho-susceptible cells or tissues.
This has resulted in identification of molecular panels that show some promise for prediction of response or for monitoring treatment outcome.
Moreover, whether it is cost effective or not, these multiplex molecular panels may obviate the need or choice to target testing to selected pathogens.
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CEO of Professional Science Editing for Scientists @ prosciediting.com