Sentence examples for molecular operative from inspiring English sources

AMPK, which is activated in mammals by metformin treatment, has also been found to be an essential molecular operative for metformin healthspan benefits in C. elegans [ 42], thus suggesting that the metformin gerosuppressant activity largely depends on its ability to engage the same metabolic sensor, i.e., AMPK, which is highly conserved across phyla.

In addition to defining molecular players operative in metformin healthspan benefits, our data suggest that metformin may be a plausible pharmacological intervention to promote healthy human aging.

Such type of analysis effectively identified and associated molecular network signatures operative in biological processes across different systems.

While the ultimate operative molecular mode through which RecA acts to control E. coli swarming motility is waiting to be disclosed, the RecA effect on swarming motility appears to be independent of an extensive canonical RecA nucleofilament formation.

Both clinicians and clinical/translational glioma researchers use the software to predict the subtypes of a given patient for the purpose of establishing the operative molecular pathways unique to that specific glioma subtype and for the purpose of identifying cohorts of patients most likely to respond to molecularly targeted agents based on our biological annotation of each subgroup.

On the basis of the present results, future studies assessing either an automated technique for mRNA quantification of PVA with QRT PCR or using one-step nucleic acid amplification (Tsujimoto et al, 2007) may pave the way towards achieving worthwhile intra-operative molecular staging of SLNs in HNSCCs.

The results of the present TF-based biophysical analysis of PPIs between GK and GKRP suggest that hepatic glucose metabolism is regulated by a metabolite-sensitive drug-responsive co-operative molecular switch, involving complex formation between these two allosterically regulated proteins.

We concluded that a synergistic effect was operative, involving molecular sieving in the nanochannels, the hydrophobicity of the non-oxide nanochannels in the membrane, and charge interaction between the solute and the membrane [33].

An important goal in future research will be to determine the ultimate molecular entity and the operative molecular mechanism through which RecA allows swarming motility in E. coli to proceed.

Venous thromboembolism risk assessment was performed for all cases, and all were prescribed post-operative low molecular weight heparin until discharge.

Therefore, understanding the molecular basis of signaling crosstalk operative in cancer cells is required to improve the existing therapies and find novel strategies to control invasive breast cancers.