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Hosseini, M. W. & De Cian, A. Crystal engineering: molecular networks based on inclusion phenomena.
Network-eligible molecules were overlaid onto molecular networks based on information from the ingenuity pathway knowledge database.
Consequently, molecular networks based on these interactions have been built to elucidate their underlying roles in biology [ 12].
A given set of input genes was associated with molecular networks based on their connectivities in the Ingenuity Pathways Knowledge Base.
This approach is distinct from other approaches that define molecular networks based on direct or indirect gene-gene interactions [ 19, 20].
Network-eligible molecules were overlaid onto molecular networks based on information from the ingenuity pathway knowledge database and networks generated based on connectivity.
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The ANDSystem package was developed for the reconstruction and analysis of molecular genetic networks based on an automated text-mining technique.
Traditional approaches to studying molecular networks are based on linking genes or proteins.
To derive the list of interacting partners of the gwas-genes, we used the VisANT tool (December 2009 version) [39], a web-enabled program for construction, visualization, and analysis of molecular and higher order networks based on functional and physical relations of the genesets.
We explored the possible biological roles of the 56 genes by performing network analysis using the commercial tool MetaCore from GeneGo Inc. which builds gene networks based on molecular interactions acquired from experiments-based literature reports [ 11].
MetaCore identifies networks based on a manually curated database containing known molecular interactions, functions, and disease interrelationships.
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