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The molecular network that controls responses to genotoxic stress is centered at p53 and Mdm2.
Based on these findings, we devised a putative molecular network that may provide a framework for the regulation of early human organogenesis.
Significant metabolites were mapped in IPA to the global molecular network that was developed from the Ingenuity Knowledge Base.
In silico analysis of the predicted gene products has implicated several processes in the complex molecular network that regulates this developmental process.
Are proteolytic enzymes lone fighters or do they have guidance to their substrates in a molecular network that builds the protease web?
Altogether, our data place Senataxin within a molecular network that preserves the integrity of replicating chromosomes and reinforce the notion that transcription represents a chronic stress for replication.
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Cellular homeostasis is regulated by signals through multiple molecular networks that include protein phosphorylation and metabolites.
The therapeutic application of these cells requires an understanding of the molecular networks that regulate pluripotency, differentiation, and de-differentiation.
This study sought to identify actionable gene targets in sarcomas by selective targeting of the molecular networks that support the growth of Ras-driven sarcomas in mice.
One lesson learned from inter-genomics studies is that there are core molecular networks that can be identified by multiple laboratories using the same platform.
We propose that studying microRNAs and their mRNA targets in the context of neurodegeneration will significantly contribute to the identification of proteins important for neuronal function and might reveal underlying molecular networks that drive these diseases.
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