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The proliferation mode is defined by the dynamics of a molecular network, such as WUS-CLV interaction in A. thaliana.
More importantly, the model identifies important components of the molecular network, such as dark reversion rate and abundance of the photoreceptor and allowed us to develop novel interpretations for the function of the stable, persistent NBs.
We hypothesized that ERα and its associated molecular network such as REarranged during Transfection (RET) tyrosine kinase and p53 may be involved in the anti-cancer effects of WA in MCF-7 breast cancer cells.
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Under the circumstances, a lot of intelligent methods have been presented to reconstruct the molecular networks, such as Boolean network and Bayesian network.
Many software packages have been developed for interactive visualization of molecular networks such as Cytoscape [ 11], Grapviz [ 12], CFinder [ 13], Tom Sawyer [ 14], VisAnt [ 15], and BiologicalNetworks [ 16].
Molecular networks, such as the KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways, aid in understanding the complex interplay of signaling pathways in disease.
In each cell, there are different kinds of molecular networks such as protein protein physical interaction networks, protein protein genetic interaction networks, regulatory networks, expression networks, signal transduction pathways, and metabolic networks (better characterized than the rest).
Several types of gene set networks have been used to study complex molecular networks such as co-membership gene set networks (M-GSNs) and co-enrichment gene set networks (E-GSNs).
Molecular networks such as protein interaction, transcriptional or metabolic networks are widely seen as integrative and coherent descriptions for the whole complement of molecular processes inside a cell [ 1].
Graph theory approach is a powerful tool for investigating the underlying global and local topological structures of molecular networks; such as, analyzing the yeast PPIN [ 1] and MN [ 2, 3].
Characterizing the changes of the molecular network during such a test is of key importance for understanding the long-term properties of different HDPE pipe grades.
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