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Upon being cross-linked sufficiently, a chemical molecular network is formed that transforms the polymer into a viscoelastic solid, which does not flow.
Using this method, it is shown that the number of active monomers in material molecular network is not necessarily a decreasing function of the applied deformation but it can even increase.
Although a strong impact of humidity on polymers and the formation of their molecular network is known, the complex interactions between humidity, temperature, diffusion, reaction kinetics, rheological behaviour and mechanical properties are not fully understood yet.
One efficient approach to identify components of a molecular network is to perform genetic modifier- or sensitized-screens [13].
While major effectors of these critical pathways have been identified, a complete understanding of this molecular network is still limited.
The molecular network is depicted in Figure 3. Here, after the binding of extracellular cAMP to the surface receptor CAR1, adenylate cyclase (ACA) activates internal cAMP.
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Importantly, the identified molecular network was found to contain complex interrelationships, providing further insight into epilepsy's underlying pathology.
Although different proteins in a molecular network are independent, they should not be considered as isolated components because they are molecularly arranged in networks in the biochemical pathways.
If the biochemical details of a chemical molecular network are known, an efficient yet detailed method for its simulation is to use chemical Monte-Carlo simulations [5], [6].
Fisher's exact tests (p = 0.05) were conducted to determine the probability that each molecular network was enriched by chance.
Such pairs of spectra connected by edges in the molecular network are revealed using the spectral alignment approach.
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