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Molecular network analyses of the identified differentially transcribed genes used Ingenuity Pathways Analysis software (Ingenuity Systems, Mountain View, CA).
Microbial MALDI-imaging mass spectrometry (IMS) coupled with molecular network analyses revealed that Pseudoalteromonas produced higher levels of antifungal polyketide alteramides in the dark than in the light.
We performed enriched biological functions and molecular network analyses using IPA (Ingenuity Pathways Analysis; Ingenuity Systems 2011), which provides a collection of gene to phenotype associations, molecular interactions, regulatory events, and chemical knowledge accumulated to develop a global molecular network.
The present study used the proteomic methods of two-dimensional gel electrophoresis (2D-DIGE), peptide mass fingerprinting via matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry (MALDI-TOF MS/MS), and bioinformatic molecular network analyses to investigate some of the complex renal protein alterations in rats after short-term hyperoxia.
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Deng, Y. et al. Molecular ecological network analyses.
We further investigated microbial assemblage architecture using random-matrix theory based molecular ecological network analyses.
Because molecular pathway or network analyses can identify biologically relevant gene interactions that might be hidden when considering only individual genes, Ingenuity Pathways Analysis software was used to analyze the 447 differentially-transcribed genes from the comparison between aCRSwNP and normal/rhinitis samples.
Studies by S. Kauffman [ 1] and R. Thomas [ 2] founded the logical discrete approach to model biological molecular networks and analyse their behaviours.
Aside from the results of our molecular phylogeny, we use phylogeographic network analyses and ENM paired with empirical ecological data in an attempt to reveal how this diversification was promoted.
Using network analyses of molecular markers, important theories can thus be tested: the technology for massive data production at an affordable price is in place, and powerful inclusive methods are available.
Network analyses revealed regulation of these molecular targets by c-myc, Her2/neu and TNF alpha, suggesting intervention with these pathways may be a promising strategy for the development of novel molecular targeted therapies for EmCa.
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