Sentence examples for molecular modification that from inspiring English sources
Ranibizumab was generated after several rounds of molecular modification that significantly increased binding affinity for its target, VEGF-A.
We move from a structural overview to the broad cellular and synaptic context of neuroligins, intermolecular interactions, and molecular modifications that occur within a synapse.
The injury begins inducing molecular modifications that subsequently evolve into cellular damage.
In vitro models have been widely used to identify the specific functions of the endothelium and to understand the molecular modifications that might occur during angiogenesis.
However, instead of protein RNA interactions, Sec body components could establish weak protein protein interactions helped by molecular modifications that could trigger conformational changes and perhaps exposure of their LCS.
Although the H5 HA cleavage motif site of MDk/W452(H5N8) bears polybasic residues denoting a high-pathogenicity phenotype in chickens, molecular modifications that are known to promote infection of mammalian hosts are not present in this virus (Supplementary Table S2).
Therefore, it seems likely that the differences in transcript profiles are age-related and reflect molecular genetic modifications that are retained during cell division.
DNA methylation is a molecular modification of DNA that is tightly associated with gene function and cell-type-specific gene function and therefore provides an exquisite identity descriptor of a cell.
A reduction in gross tumour size is delayed and lags behind these early biological and molecular modifications, so that clinical response criteria defined by size alone can be misleading.
The researchers examined patterns of DNA methylation – a molecular modification to DNA that affects when and how strongly a gene is expressed – across the genome in pairs of identical male twins.
One hypothesis is that CRFR1-coupled Gβγ subunits have a unique molecular property (i.e. post-translational modification) that facilitates activation of downstream signaling pathways.
