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Therefore, it is reasonable to design scores to evaluate the reproducibility of disease signatures of cancers at multiple levels based on some biological assumptions (or molecular models), taking into account functional relations between the disease signatures such as expression correlation [ 16] and functional similarity [ 25].
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To address this, Dr. Zheng Guo (Harbin Medical University) proposed a new strategy of using scores to evaluate the functional reproducibility of cancer biomarkers based on molecular models that take into account the functional associations among the marker genes/proteins.
47 models took part, featuring 81 looks.
Since SLN in mouse models takes 6-12 montos to manifest, the experimental anti-GBM nephritis model has been used as a useful tool to unravel the molecular basis of SLN.
A simple model taking into account the molecular volume of the adsorbent and of water molecules could explain the measured mass loss.
The structure of the networks was predicted with a molecular model based on a mean field approach (recursive model) taking into account the initial composition of the reactants.
However, the best fits are attained when some of the molecular parameters of the model take inappropriate values.
After the expo closes for judging, visitors can do science themselves, including building molecular models, undertaking challenges in "Phun With Physics" and taking a tour of the brain via slides and computerized images.
At the same time, our model takes into account only the intra-molecular factors that are encoded in the protein chain.
Some attempts have already been made towards designing new catB inhibitors using molecular modeling techniques [ 24, 25], taking into account dynamical aspects of binding.
Our model takes its structure from the network topology suggested by molecular biology experiments conducted using cultured neurons [ 17, 19, 24, 35].
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