Sentence examples for molecular modeling guided from inspiring English sources

Molecular modeling guided the design of the series.

The results from molecular modeling will guide the design of novel hCPTs with higher antitumor activity.

As a first step, we describe molecular modeling to guide focused chemical syntheses of conjugates having nucleoside (d4T) and nonnucleoside (TIBO) moieties tethered by a flexible polyethylene glycol (PEG) linker.

The objectives of the present study were first to identify the MHC and TCR contact residues in the RA-associated epitope using a panel of well-characterized specific T cell hybridomas, second to derive a molecular model to guide APL design, and third, to identify an APL capable of modulating the pro-inflammatory response to the synovial auto-epitope.

We validated the roles of TFs and effector molecules in PCa metastasis with in vivo animal models guided by molecular imaging where abrogating RANK or its downstream c-Myc/Max or c-Met signaling network abolished skeletal metastasis in mice.

We suggest that these developments are gradually leading to a change in emphasis of early clinical trials to a therapeutic model guided by the molecular classification of tumours.

Disulfide trapping can serve at least two distinct purposes: (i) stabilization of the complex to assist structural studies and/or (ii) determination of pairwise residue proximities to guide molecular modeling.

This model guided our research.

A modified Health behaviour model guided our analytical approach.

Here, we report the humanization of mouse 38C2 based on rational design guided by molecular modeling.

Guided by molecular modeling and docking a series of etoposide analog epipodophyllotoxin N-mustard hybrid compounds wepipodophyllotoxin N-mustardd biologically chybriderized.