Michels, B. et al. Cellular site and molecular mode of synapsin action in associative learning.
BAY 2402234 binds the ubiquinone binding site of DHODH between the N-terminal helices (Helix A & B), thereby demonstrating its molecular mode of action.
Our results provide insights into the molecular mode of action by which TR-lincRNAs contribute to complex human traits.
The ability of Cannabis sativa (marijuana) to increase hunger has been noticed for centuries, although intensive research on its molecular mode of action started only after the characterization of its main psychoactive component Δ9-tetrahydrocannabinol in the late 1960s.
Here, we show how humanization of mAb 85RF45.1 into mAb TB31F retained the exact molecular mode of recognition of Pfs48/45, its high-affinity binding to the antigen, and its potent transmission-reducing activity in SMFA.
The molecular mode of action revealed that 13c caused cell-cycle arrest at S phase and induced apoptosis in Bel-7402 cells through mitochondria-related caspase-dependent pathways.
The aim of present study was to characterize the molecular mode of action (MoA) of the ER agonist 17α-ethinylestradiol (EE2) in primary rainbow trout (Oncorhynchus mykiss) hepatocytes.
In this review, an attempt has been made to elucidate the molecular mode of action of various plant products, and synthetic drugs investigated in various preclinical and clinical tests in AD.
Insight into the structure activity relationships of the A-ring of 1 is still needed to assist the development of more potent and selective analogues as candidate chemotherapeutic agents, as well as to define the molecular mode of action.
As we continue to be embroiled in the global battle against the human immunodeficiency virus (HIV), there has been an ongoing evolution in the understanding of the molecular mode of sexual transmission of HIV.
