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To address whether common molecular mechanisms regulate nerve cord formation during arthropod nervous system development, we recently analyzed patterns of axon tract formation and the putative homology of midline cells in distantly related arthropods.
Although some candidate CNVs may reflect amplification dropout artifacts, the neuron-lymphoblast differences suggest that distinct molecular mechanisms regulate formation of CNVs in these two cell types.
Together, these results suggest that different molecular mechanisms regulate PGC development in the embryos of mouse and humans, and it is not yet clear which, if either, of these modes is more widespread among mammals.
Altogether, this is an excellent paper that explores the role of a key epigenetic regulator in NSC populations in the adult SVZ and in the process reveals that distinct molecular mechanisms regulate NSC proliferation and neurogenic capacity.
These observations suggest a dose-dependent requirement of Lhx6 for the differentiation of Sst+ and Pva+ cortical interneurons and provide independent genetic evidence that distinct molecular mechanisms regulate the differentiation of cortical interneuron subclasses.
The expression profiles in muscles from OPMD and elderly are highly similar, despite the average age difference of 30 years, suggesting that common molecular mechanisms regulate these genome-wide transcriptional changes.
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Arabidopsis thaliana, a typical herbaceous dicot, has been employed as a model plant to study the molecular mechanisms regulating the initiation, development and regulation of the vascular system.
The cellular and molecular mechanisms regulating these different developmental decisions are still unclear.
Unfortunately, little is known about the molecular mechanisms regulating this adaptive response.
Development of more differentiated podocytes in culture has dramatically increased our understanding of the molecular mechanisms regulating podocyte actin dynamics.
This article describes the experimental strategies that have been utilized to begin unraveling the molecular mechanisms regulating the functional activity of RGS-containing RhoGEFs.
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